Limited to 300 copies. A history of the first medical book printed in California, the Botica General De Los Remedios Esperimentados. This book was printed by California's first printer, Agustín Vicente Zamorano on a Ramage wooden press imported from Boston in 1834. With a woodcut showing a Ramage Press, a facsimile of Zamorano's signature and printing and design by Richard J. Hoffman. With a facsimile of the pamphlet reproduced from one of two known copies loosely inserted in a pocket in the front.